To understand how Klipper is working you may want to read Klipper Architecture / Ecosystem. In short:
- Both the LIS sensors are already using their own RPi Pico MCU (RP2040) that does manage this single sensor and is 99% bored with it
- The data from these MCUs is crunched on the RPi 4B you are using as host and this is the very task of the host
So, no, it makes no sense to distribute the sensors to other RPis.
To be honest, I just copied it from the BTT default example. It does not really matter regarding the computed results.
Where it might be a thing is when you graph the results and see that, e.g. X and Y are switched etc.
If you take a look at the sensor, you will see some coordinate system. You can use this setting to align with your actual movement direction:
