No - the current code only supports the first 30 gpio pins. As I understand it, it should be possible to bootup an RP2350B chip with the current code, but gpios>30 wont work and neither will any of the adc pins.
If you (or someone else) has access to an RP2350B and are willing to run tests, then I can probably send over development code. If interested, verify the current code flashes and boots with the current code, and then attach the full klipper log here.
Cheers,
-Kevin