From a brief look, it is not an “expander” in the sense chip that can multiplex/switch channels.
It is just a board with mcu.
So it is just an MCU with a board, same as any for any 3d printer.
So, IDK about this specific AT20 sensor if there is a code to support it (Maybe it is compatible with HTU21, who knows?).
But any I2C device would simply connect to the bus:
*as long as there is no address clash, you can virtually add up to 127 devices.
(There is a limit though, with bus capacitance and pull-up resistance, if you decide to add too much devices).