if no one answered your question, I have several of the 2.2.x boards incliding one in my sv03, and indeed its klipper compaitble. the issue I believe your referring to is the UART pins are hard wired on the mobo, also you adjust the Vref with a multimeter and a screwdriver.
So we leave out the advanced [tmc2208] config for those and your fine.
The Silent motherboards have TMC2208_STANDALONE drivers and cant (without hardware mods) set advanced features in klipper.
(see pic and link to an example hardware mod to enable uart pins on the 4.2.x)
but an example on 2208 boards that do have uart control, the uart pin and advanced controls is defined here:
[tmc2208 stepper_z]
uart_pin: P1.10
microsteps: 16
interpolate: True
hold_current: 0.5
run_current: 0.7
stealthchop_threshold: 200
driver_PWM_AUTOGRAD: True
driver_PWM_AUTOSCALE: True
driver_HEND: 3
driver_HSTRT: 0
We just leave it out..
I do like the 2.2.1 board I have as it has all 5 stepper drivers and heatsyncs. which let me switch around the steppers; as I have independant z motors now running in Klipper, I moved them to the Y and E1 ports, I also moved the Y to the dual z port, in anticipation of going dual Y motors. the huge 350x350 Glass bed weights alot and have to keep accels low.
So now I have X,Z,Yy,E0,Z1 (and of course I adjusted the vrefs to match. )
(edit: I realize this is older post so appologize if you’ve already gotten your answer, but hate to have someone not going klipper thinking its not compatible with the board.)