Getting orange pi 3 lts + klipper working with anycubic kobra 2 neo

No, the error is not the same.

First log:

mcu 'mcu': Unable to open serial port: [Errno 13] could not open port /dev/serial/by-id/usb-1a86_USB_Serial-if00-port0: [Errno 13] Permission denied: '/dev/serial/by-id/usb-1a86_USB_Serial-if00-port0'

Second log:

mcu 'mcu': Timeout on connect
MCU error during connect
...
serialhdl.error: mcu 'mcu': Unable to connect

Which would indicate that the board is not correctly flashed. Check with How-To Trouble-Shoot to see if and how the board registers to the Linux OS

As for the Kobra 2 Neo, I would not be aware of an existing config file and build instructions, so I do not know on which reference you build it.

From your log

========= Last MCU build config =========
CONFIG_LOW_LEVEL_OPTIONS=y
# CONFIG_MACH_AVR is not set
# CONFIG_MACH_ATSAM is not set
# CONFIG_MACH_ATSAMD is not set
# CONFIG_MACH_LPC176X is not set
# CONFIG_MACH_STM32 is not set
# CONFIG_MACH_HC32F460 is not set
# CONFIG_MACH_RP2040 is not set
# CONFIG_MACH_PRU is not set
# CONFIG_MACH_AR100 is not set
# CONFIG_MACH_LINUX is not set
CONFIG_MACH_SIMU=y
CONFIG_BOARD_DIRECTORY="simulator"
CONFIG_CLOCK_FREQ=20000000
CONFIG_SERIAL=y
CONFIG_SIMULATOR_SELECT=y
CONFIG_SERIAL_BAUD=115200
CONFIG_USB_VENDOR_ID=0x1d50
CONFIG_USB_DEVICE_ID=0x614e
CONFIG_USB_SERIAL_NUMBER="12345"
CONFIG_WANT_GPIO_BITBANGING=y
CONFIG_WANT_DISPLAYS=y
CONFIG_WANT_SENSORS=y
CONFIG_WANT_LIS2DW=y
CONFIG_WANT_SOFTWARE_SPI=y
CONFIG_CANBUS_FREQUENCY=1000000
CONFIG_INITIAL_PINS=""
CONFIG_HAVE_GPIO=y
CONFIG_HAVE_GPIO_ADC=y
CONFIG_HAVE_GPIO_SPI=y
CONFIG_HAVE_GPIO_HARD_PWM=y
CONFIG_INLINE_STEPPER_HACK=y

These make menuconfig parameters definitively are wrong, but since I do not have better ones, I cannot provide further guidance.