I did a lot of testing in another thread(Impossible Bed mesh leveling - Cr10sPro V2) and in the end I found the only way I could get a reliable first layer printer was to run a mesh calibrate(BED_MESH_CALIBRATE PROFILE=) after the G28 for each print. I was seeing similar results as you are when I just loaded the profile. It doesn’t make sense to me but those were the results I saw.
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